This makes it helpful in treating conditions including chronic bronchitis (defined as the presence of chronic productive coughs for more than three months in two consecutive years), as well as colds and the flu. NAC has the ability to reduce mucus secretions and phlegm, as well as to reduce coughing, wheezing and trouble breathing. Helps Treat Respiratory Issues by Breaking Up Mucus Doses of about 0.6 grams of NAC daily can be taken orally along with progesterone after week 16 of pregnancy in order to protect against preterm birth recurrence.Īdditionally, it can help treat acetaminophen overdose during pregnancy, which is the most common drug overdose reported among pregnant women. NAC also has anti-inflammatory effects that can improve pregnant and birth outcomes among women with infections, who are susceptible to experiencing preterm labors. This is because it increases levels of the antioxidant glutathione, which positively acts on insulin secretion and reduces insulin resistance, which is believed to be associated with PCOS.Īccording to an article published in Women’s Health Reviews, NAC seems to work as a therapeutic approach to improve the level of circulating insulin, as well as insulin sensitivity, in PCOS patients with hyperinsulinemia. Is N-acetyl cysteine safe during pregnancy? Studies have shown no maternal or fetal harmful effects of NAC treatment.Ĭertain studies have even found that NAC used in combination with vitamin E, or vitamins A and E, and essential fatty acids can reduce reactive oxygen species (ROS) and lead to pregnancy rate improvements in those struggling to become and stay pregnant, especially women with PCOS. This is why it’s recommended as a potential treatment for different disorders resulting from free oxygen radicals, such as liver disease, Alzheimer’s, Parkinson’s and even cancer. These are due to its ability to increase glutathione levels, scavenge free radicals and reduce oxidative stress. The most important N-acetyl cysteine mechanisms of action are its antioxidant and anti-inflammatory effects. In other words, as a precursor of L-cysteine, which results in glutathione biosynthesis, NAC (along with glutamine and glycine) is an amino acid that is needed to produce what’s arguably the most important antioxidant in the human body. NAC is involved in the regulation of the glutamatergic system. Has Antioxidant Effects and Helps Form Glutathione What is NAC used for? See the multiple potential NAC benefits below. While cysteine is found in many high-protein foods, NAC is only obtained from taking supplements or prescription drugs.īecause the human body can create some NAC from other amino acids, particularly l-methionine and l-serine, it is considered to be a “semi-essential amino acid.” That means there isn’t a daily requirement of NAC that you must get from your diet, but getting higher amounts can benefit some people. N-acetyl cysteine, the supplement form of cysteine, is an amino acid that helps the body create and use protective antioxidants. What are the benefits of taking NAC? Not only has been it been used for three decades as an effective mucolytic agent (mucous-thinner), but it also has uses including reducing inflammation, protecting the liver, and preventing/treating drug toxicity, insulin resistance, infertility due to PCOS and more. Research suggests that N-acetyl cysteine (NAC) - the supplement form of the semi-essential amino acid L-cysteine - is an effective, safe and low-cost treatment option for a range of conditions, including those that are both acute and chronic.
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